Unità di Ricerca: Unità di Medicina Molecolare
Coordinatore: Prof Francesco Cipollone
Sede Universitaria: Università di Chieti G. d’Annunzio”, Dipartimento di Medicina e Scienze dell’Invecchiamento
Indirizzo: Via dei Vestini, 66013, Chieti
tel: 0871/358058
fax: 0871/358058
e-mail: francesco.cipollone@unich.it
Linee di ricerca: Meccanismi molecolari alla base dell’instabilità della placca nel contesto dei principali fattori di rischio cardiovascolari: ipertensione, ipercolesterolemia, diabete.
Laboratori/strumentazione:
| LABORATORI | STRUMENTAZIONE |
| Laboratorio di Medicina Molecolare | Centrifuga, pompa da vuoto, trappola refrigerata, cappe, citofluorimetro, microscopio confocale, spettrofotometro, Real-time PCR, lettori ELISA |
Collaborazioni internazionali:
- William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, London, UK.
- Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
- Donald W. Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
- Eccles Institute of Human Genetics, Salt Lake City, Utah 84112, USA.
Elenco pubblicazioni del triennio 2016 – 2018:
Tana C, Silingardi M, Giamberardino MA, Cipollone F, Meschi T, Schiavone C. Emphysematous pancreatitis associated with penetrating duodenal ulcer.World J Gastroenterol. 2017 Dec 28;23(48):8666-8670.
Giamberardino MA, Affaitati G, Costantini R, Cipollone F, Martelletti P. Calcitonin gene-related peptide receptor as a novel target for the management of people with episodic migraine: current evidence and safety profile of erenumab. J Pain Res. 2017 Dec 8;10:2751-2760
Della Pelle C, Orsatti V, Cipollone F, Cicolini G. Health literacy among caregivers of patients with heart failure: A multicentre cross-sectional survey. J Clin Nurs. 2018 Feb;27(3-4):859-865
Pirillo A, Garlaschelli K, Arca M, Averna M, Bertolini S, Calandra S, Tarugi P, Catapano AL; LIPIGEN Group. Spectrum of mutations in Italian patients with familial hypercholesterolemia: New results from the LIPIGEN study. Atheroscler Suppl. 2017 Oct;29:17-24.
Averna M, Cefalù AB, Casula M, Noto D, Arca M, Bertolini S, Calandra S, Catapano AL, Tarugi P; LIPIGEN Group. Familial hypercholesterolemia: The Italian Atherosclerosis Society Network (LIPIGEN). Atheroscler Suppl. 2017 Oct;29:11-16.
De Iuliis V, Ursi S, Pennelli A, Caruso M, Nunziata A, Marino A, Flati V, Cipollone F, Giamberardino MA, Vitullo G, Toniato E, Conti P, Martinotti S. Differential TBXA2 receptor transcript stability is dependent on the C924T polymorphism. Prostaglandins Other Lipid Mediat. 2018 Jan;134:141-147.
Violi F, Targher G, Vestri A, Carnevale R, Averna M, Farcomeni A, Lenzi A, Angelico F, Cipollone F, Pastori D.Effect of aspirin on renal disease progression in patients with type 2 diabetes: A multicenter, double-blind, placebo-controlled, randomized trial. The renaL disEase progression by aspirin in diabetic pAtients (LEDA) trial. Rationale and study design. Am Heart J. 2017 Jul;189:120-127.
De Iuliis V, Ursi S, Vitullo G, Griffo I, Marino A, Caruso M, Cipollone F, Capodifoglio S, Breda V, Toniato E, Pennelli A, Conti P, Martinotti S. Analytical Management of Patients Undergoing Oral Anticoagulant Therapy Could Have a Strong Impact on Clinical Outcomes: A Follow-up Study. Cardiol Ther. 2017 Dec;6(2):261-271.
Affaitati G, Martelletti P, Lopopolo M, Tana C, Massimini F, Cipollone F, Lapenna D, Giamberardino MA, Costantini R. P003. NSAIDs for symptomatic treatment of headache. J Headache Pain. 2015 Dec;16(Suppl 1):A162.
Bucci M, Tana C, Giamberardino MA, Cipollone F. Lp(a) and cardiovascular risk: Investigating the hidden side of the moon. Nutr Metab Cardiovasc Dis. 2016 Nov;26(11):980-986.
Tana C, Giamberardino MA, Cipollone F. microRNA profiling in atherosclerosis, diabetes, and migraine. Ann Med. 2017 Mar;49(2):93-105.
Affaitati G, Martelletti P, Lopopolo M, Tana C, Massimini F, Cipollone F, Lapenna D, Giamberardino MA, Costantini R. Use of Nonsteroidal Anti-Inflammatory Drugs for Symptomatic Treatment of Episodic Headache. Pain Pract. 2017 Mar;17(3):392-401.
Santilli F, Boccatonda A, Davì G, Cipollone. The Coxib case: Are EP receptors really guilty? Atherosclerosis. 2016 Jun;249:164-73.
Giamberardino MA, Affaitati G, Martelletti P, Tana C, Negro A, Lapenna D, Curto M, Schiavone C, Stellin L, Cipollone F, Costantini R. Impact of migraine on fibromyalgia symptoms. J Headache Pain. 2015;17:28.
Iuvone T, Affaitati G, De Filippis D, Lopopolo M, Grassi G, Lapenna D, Negro L, Costantini R, Vaia M, Cipollone F, Ialenti A, Giamberardino MA. Reply. Pain. 2016 Mar;157(3):770-1.
Kok MG, Mandolini C, Moerland PD, de Ronde MW, Sondermeijer BM, Halliani A, Nieuwland R, Cipollone F, Creemers EE, Meijers JC, Pinto-Sietsma SJ. Low miR-19b-1-5p expression in isolated platelets after aspirin use is related to aspirin insensitivity. Int J Cardiol. 2016 Jan 15;203:262-3.