Unità di Ricerca: Cardiologia, Università di Palermo

Responsabile/Coordinatore: Prof. Giuseppina Novo
Sede Universitaria Università di Palermo
Dipartimento PROMISE
Indirizzo: Piazza delle Cliniche, Palermo, 90100

tel: 0916554536

e-mail:  giuseppina.novo@unipa.it

sito web:

Linee di ricerca: Cardio-oncologia, Scompenso cardiac, cardiomiopatie miocarditi, studiod ella funzione micoardica, S. Takotsubo


Laboratori/strumentazione: Ambulatori dedicati allo scompenso, valvulopatie, cardio-oncologia, cardiomiopatie, cardiopatia ischemica, ecocardiografia transesofagea ed eco-stress con ecocardiografi Phlips Epic e Vivd 7.


Collaborazioni internazionali:

Council of Cardio-Oncology, GEIST

Elenco ultime pubblicazioni:

1. Cardiovascular Biomarkers in Cardio-Oncology: Antineoplastic Drug Cardiotoxicity and Beyond.

Attanasio U, Di Sarro E, Tricarico L, Di Lisi D, Armentaro G, Miceli S, Fioretti F, Deidda M, Correale M, Novo G, Sciacqua A, Nodari S, Cadeddu C, Tocchetti CG, Palazzuoli A, Mercurio V.

Biomolecules. 2024 Feb 7;14(2):199. doi: 10.3390/biom14020199.

PMID: 38397436 Free PMC article. Review.

2. Neurological Disorders in Takotsubo Syndrome: Clinical Phenotypes and Outcomes.

Santoro F, Núñez Gil IJ, Arcari L, Vitale E, Martino T, El-Battrawy I, Guerra F, Novo G, Mariano E, Musumeci B, Cacciotti L, Caldarola P, Montisci R, Ragnatela I, Cetera R, Vedia O, Blanco E, Pais JL, Martin A, Pérez-Castellanos A, Salamanca J, Bartolomucci F, Akin I, Thiele H, Eitel I, Stiermaier T, Brunetti ND.

J Am Heart Assoc. 2024 Feb 20;13(4):e032128. doi: 10.1161/JAHA.123.032128. Epub 2024 Feb 14.

PMID: 38353238 Free article.

3. Age-Related Differences in Takotsubo Syndrome: Results From the Multicenter GEIST Registry.

El-Battrawy I, Santoro F, Núñez-Gil IJ, Pätz T, Arcari L, Abumayyaleh M, Guerra F, Novo G, Musumeci B, Cacciotti L, Mariano E, Caldarola P, Parisi G, Montisci R, Vitale E, Volpe M, Corbì-Pasqual M, Martinez-Selles M, Almendro-Delia M, Sionis A, Uribarri A, Thiele H, Brunetti ND, Eitel I, Akin I, Stiermaier T.

J Am Heart Assoc. 2024 Feb 20;13(4):e030623. doi: 10.1161/JAHA.123.030623. Epub 2024 Feb 13.

PMID: 38348805 Free article.

4. Evaluation and management of patients with coronary chronic total occlusions considered for revascularisation. A clinical consensus statement of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC, the European Association of Cardiovascular Imaging (EACVI) of the ESC, and the ESC Working Group on Cardiovascular Surgery.

Galassi AR, Vadalà G, Werner GS, Cosyns B, Sianos G, Hill J, Dudek D, Picano E, Novo G, Andreini D, Gerber BLM, Buechel R, Mashayekhi K, Thielmann M, McEntegart MB, Vaquerizo B, Di Mario C, Stojkovic S, Sandner S, Bonaros N, Lüscher TF.

EuroIntervention. 2024 Feb 5;20(3):e174-e184. doi: 10.4244/EIJ-D-23-00749.

PMID: 38343372 Free article.

5. The added value of the HFA/ICOS score in the prediction of chemotherapy-related cardiac dysfunction in breast cancer.

Di Lisi D, Madaudo C, Faro DC, Rossetto L, Triolo OF, Losi V, Galassi AR, Monte IP, Novo G.

J Cardiovasc Med (Hagerstown). 2024 Mar 1;25(3):218-224. doi: 10.2459/JCM.0000000000001589. Epub 2024 Feb 2.

PMID: 38305134

6. Improving cardiovascular health today to prevent heart failure tomorrow: The importance of a holistic approach.

Madaudo C, Bromage D, Novo G, Cannata A.

Eur J Prev Cardiol. 2024 Jan 22:zwae023. doi: 10.1093/eurjpc/zwae023. Online ahead of print.

PMID: 38253340 No abstract available.

7. Management of cancer patients at high and very-high risk of cardiotoxicity: Main questions and answers.

Di Lisi D, Cadeddu Dessalvi C, Zito C, Madaudo C, Manganaro R, Mercurio V, Deidda M, Santoro C, Penna C, Monte IP, Spallarossa P, Tocchetti CG, Novo G.

Curr Probl Cardiol. 2024 Mar;49(3):102229. doi: 10.1016/j.cpcardiol.2023.102229. Epub 2023 Dec 27.

PMID: 38154703 Free article. Review.

8. Statin therapy and outcome in Takotsubo syndrome patients: Results from the multicenter international GEIST registry.

Novo G, Arcari L, Stiermaier T, Alaimo C, El-Battrawy I, Cacciotti L, Guerra F, Musumeci B, Mariano E, Parisi G, Montisci R, Vazirani R, Perez Castellanos A, Uribarri A, Corbi-Pascual M, Salamanca J, Akin I, Thiele H, Brunetti ND, Eitel I, Núñez Gil IJ, Santoro F.

Atherosclerosis. 2024 Feb;389:117421. doi: 10.1016/j.atherosclerosis.2023.117421. Epub 2023 Dec 13.

PMID: 38134646 Free article.

9. Hereditary Transthyretin Amyloidosis: How to Differentiate Carriers and Patients Using Speckle-Tracking Echocardiography.

Di Lisi D, Brighina F, Manno G, Comparato F, Di Stefano V, Macaione F, Damerino G, Di Caccamo L, Cannizzo N, Ortello A, Galassi AR, Novo G.

Diagnostics (Basel). 2023 Dec 9;13(24):3634. doi: 10.3390/diagnostics13243634.

PMID: 38132218 Free PMC article.

10. Anthracycline-related cardiotoxicity in patients with breast cancer harboring mutational signature of homologous recombination deficiency (HRD).

Incorvaia L, Badalamenti G, Novo G, Gori S, Cortesi L, Brando C, Cinieri S, Curigliano G, Ricciardi GR, Toss A, Chiari R, Berardi R, Ballatore Z, Bono M, Bazan Russo TD, Gristina V, Galvano A, Damerino G, Blasi L, Bazan V, Russo A.

11. ESMO Open. 2024 Jan;9(1):102196. doi: 10.1016/j.esmoop.2023.102196. Epub 2023 Dec 19.European Society of Cardiology Core Curriculum for cardio-oncology.

López-Fernández T, Farmakis D, Ameri P, Asteggiano R, de Azambuja E, Aznar M, Barac A, Bayes-Genis A, Bax JJ, Bergler-Klein J, Boriani G, Celutkiene J, Coats A, Cohen-Solal A, Córdoba R, Cosyns B, Filippatos G, Fox K, Gulati G, Inciardi RM, Lee G, Mamas MA, Novo G, Plummer C, Psyrri A, Rakisheva A, Suter T, Tini G, Tocchetti CG, Toutouzas K, Wilhelm M, Metra M, Lyon AR, Rosano GMC.

Eur J Heart Fail. 2023 Dec 7. doi: 10.1002/ejhf.3102. Online ahead of print.

PMID: 38059343

12. Smoking influence in Takotsubo syndrome: insights from an international cohort.

Núñez-Gil IJ, Santoro F, Vazirani R, Novo G, Blanco-Ponce E, Arcari L, Uribarri A, Cacciotti L, Guerra F, Salamanca J, Musumeci B, Vedia O, Mariano E, Fernández-Cordón C, Caldarola P, Montisci R, Brunetti ND, El-Battrawy I, Abumayyaleh M, Akin I, Eitel I, Stiermaier T.

Front Cardiovasc Med. 2023 Nov 20;10:1282018. doi: 10.3389/fcvm.2023.1282018. eCollection 2023.

PMID: 38054096 Free PMC article.

13. Atrial Strain Assessment for the Early Detection of Cancer Therapy-Related Cardiac Dysfunction in Breast Cancer Women (The STRANO STUDY: Atrial Strain in Cardio-Oncology).

Di Lisi D, Moreo A, Casavecchia G, Cadeddu Dessalvi C, Bergamini C, Zito C, Madaudo C, Madonna R, Cameli M, Novo G.

J Clin Med. 2023 Nov 16;12(22):7127. doi: 10.3390/jcm12227127.

PMID: 38002739 Free PMC article.

14. Clinical Outcomes and Quality of Life after Patent Foramen Ovale (PFO) Closure in Patients with Stroke/Transient Ischemic Attack of Undetermined Cause and Other PFO-Associated Clinical Conditions: A Single-Center Experience.

Evola S, Camarda EA, Triolo OF, Adorno D, D’Agostino A, Novo G, Onorato EM.

J Clin Med. 2023 Sep 5;12(18):5788. doi: 10.3390/jcm12185788.

PMID: 37762729 Free PMC article.

15. Genetic screening for hereditary transthyretin amyloidosis with polyneuropathy in western Sicily: Two years of experience in a neurological clinic.

Di Stefano V, Lupica A, Alonge P, Pignolo A, Augello SM, Gentile F, Gagliardo A, Giglia F, Brinch D, Cappello M, Di Lisi D, Novo G, Borgione E, Scuderi C, Brighina F.

Eur J Neurol. 2024 Jan;31(1):e16065. doi: 10.1111/ene.16065. Epub 2023 Sep 19.

PMID: 37725003

16. Subclinical Atrial Fibrillation on Prolonged ECG Holter Monitoring: Results from the Multicenter Real-World SAFARI (Silent Atrial Fibrillation ANCE-Sicily Research Initiative) Study.

de Gregorio C, Di Franco A, Panno AV, Di Franco M, Scaccianoce G, Campanella F, Novo G, Galassi AR, Novo S, The Safari Study Group.

J Cardiovasc Dev Dis. 2023 Aug 4;10(8):336. doi: 10.3390/jcdd10080336.

PMID: 37623349 Free PMC article.

17. Chemotherapy-related cardiac dysfunction: the usefulness of myocardial work indices.

Di Lisi D, Manno G, Madaudo C, Filorizzo C, Intravaia RCM, Galassi AR, Incorvaia L, Russo A, Novo G.

Int J Cardiovasc Imaging. 2023 Oct;39(10):1845-1853. doi: 10.1007/s10554-023-02897-9. Epub 2023 Aug 7.

PMID: 37548845

18. Arterial hypertension in patients with takotsubo syndrome: prevalence, long-term outcome, and secondary preventive strategies: a report from the Takotsubo Italian Network register.

Silverio A, Bossone E, Parodi G, Scudiero F, Di Maio M, Vriz O, Bellino M, Zito C, Provenza G, Iuliano G, Cristiano M, Novo G, Mauro C, Rigo F, Innelli P, Salerno-Uriarte J, Cameli M, Tremiterra G, Vecchione C, Antonini-Canterin F, Galasso G, Citro R.

Eur J Prev Cardiol. 2023 Dec 21;30(18):1998-2005. doi: 10.1093/eurjpc/zwad237.

PMID: 37463434

19. Trigger-Associated Clinical Implications and Outcomes in Takotsubo Syndrome: Results From the Multicenter GEIST Registry.

Pätz T, Santoro F, Cetera R, Ragnatela I, El-Battrawy I, Mezger M, Rawish E, Andrés-Villarreal M, Almendro-Delia M, Martinez-Sellés M, Uribarri A, Pérez-Castellanos A, Guerra F, Novo G, Mariano E, Musumeci MB, Arcari L, Cacciotti L, Montisci R, Akin I, Thiele H, Brunetti ND, Vedia O, Núñez-Gil IJ, Eitel I, Stiermaier T.

J Am Heart Assoc. 2023 Jul 18;12(14):e028511. doi: 10.1161/JAHA.122.028511. Epub 2023 Jul 8.

PMID: 37421264 Free PMC article.

20. Impact of intra-aortic balloon counterpulsation on all-cause mortality among patients with Takotsubo syndrome complicated by cardiogenic shock: results from the German-Italian-Spanish (GEIST) registry.

Santoro F, Núñez Gil IJ, Stiermaier T, El-Battrawy I, Moeller C, Guerra F, Novo G, Arcari L, Musumeci B, Cacciotti L, Mariano E, Romeo F, Cannone M, Caldarola P, Giannini I, Mallardi A, Leopizzi A, Vitale E, Montisci R, Meloni L, Raimondo P, Di Biase M, Almendro-Delia M, Sionis A, Uribarri A, Akin I, Thiele H, Eitel I, Brunetti ND.

Eur Heart J Open. 2023 Jan 24;3(1):oead003. doi: 10.1093/ehjopen/oead003. eCollection 2023 Jan.

21. Longitudinal Strain Analysis and Correlation with TIMI Frame Count in Patients with Ischemia with No Obstructive Coronary Artery (INOCA) and Microvascular Angina (MVA).

Sucato V, Novo G, Madaudo C, Di Fazio L, Vadalà G, Caronna N, D’Agostino A, Evola S, Tuttolomondo A, Galassi AR.

J Clin Med. 2023 Jan 19;12(3):819. doi: 10.3390/jcm12030819.

PMID: 36769468 Free PMC article.

22. Presentation, care, and outcomes of patients with NSTEMI according to World Bank country income classification: the ACVC-EAPCI EORP NSTEMI Registry of the European Society of Cardiology.

Nadarajah R, Ludman P, Laroche C, Appelman Y, Brugaletta S, Budaj A, Bueno H, Huber K, Kunadian V, Leonardi S, Lettino M, Milasinovic D, Gale CP; NSTEMI investigator group.

Eur Heart J Qual Care Clin Outcomes. 2023 Sep 12;9(6):552-563. doi: 10.1093/ehjqcco/qcad008.

PMID: 36737420 Free PMC article.

23. Higher Incidence of Cancer Therapy-Related Cardiac Dysfunction in the COVID-19 Era: A Single Cardio-Oncology Center Experience.

Di Lisi D, Madaudo C, Di Fazio L, Gulotta A, Triolo OF, Galassi AR, Incorvaia L, Russo A, Novo G.

J Cardiovasc Dev Dis. 2023 Jan 6;10(1):23. doi: 10.3390/jcdd10010023.

PMID: 36661918 Free PMC article.

24. Deformation Imaging by Strain in Chronic Heart Failure Over Sacubitril-Valsartan: A Multicenter Echocardiographic Registry.

Mandoli GE, Pastore MC, Giannoni A, Benfari G, Dini FL, Rosa G, Pugliese NR, Taddei C, Correale M, Brunetti ND, Mazzeo P, Carluccio E, Mengoni A, Guaricci AI, Piscitelli L, Citro R, Ciccarelli M, Novo G, Corrado E, Pasquini A, Loria V, De Carli G, Degiovanni A, Patti G, Santoro C, Moderato L, Cicoira M, Canepa M, Malagoli A, Emdin M, Cameli M.

ESC Heart Fail. 2023 Apr;10(2):846-857. doi: 10.1002/ehf2.14155. Epub 2022 Nov 29.

PMID: 36448244 Free PMC article.

25. Therapy of ATTR Cardiac Amyloidosis: Current Indications.

Di Lisi D, Di Stefano V, Brighina F, Galassi AR, Novo G.

Curr Probl Cardiol. 2023 Feb;48(2):101487. doi: 10.1016/j.cpcardiol.2022.101487. Epub 2022 Nov 4. PMID: 36336119 Review.

26. Management of a patient with multiple device replacements and extractions: When the leadless pacemaker is a viable solution.

Coppola G, Ciaramitaro G, Madaudo C, Di Caccamo L, Testa G, Castelluccio E, Rizzuti G, Torre S, Novo G, Galassi AR, Corrado E.

Pacing Clin Electrophysiol. 2023 Mar;46(3):268-270. doi: 10.1111/pace.14605. Epub 2022 Nov 9.

PMID: 36269180